Palumbo 2015 R-ISS for multiple myeloma
Palumbo 2015 R-ISS for multiple myeloma. ISS from beta-2 microglobulin and albumin (Greipp 2005). R-ISS I: ISS I, standard-risk iFISH CA, and normal LDH. R-ISS III: ISS III plus high-risk CA (del(17p) and/or t(4;14) and/or t(14;16)) or LDH > ULN. R-ISS II: all other combinations. Not a myeloma diagnosis or treatment choice; not R2-ISS; not Durie-Salmon. magent does not assay beta-2 microglobulin, albumin, LDH, or cytogenetics.
Answeringour last check, 2026-09-28
1 of 1checks answered this week
266 msmedian answer time
$0.005listed price per call
$0.005price it asked us
Paid test badge: not yet. The checks above are free: we call the tool without paying and read the payment request it sends back. The Verified badge needs paid calls whose answers match the promised output, and nobody can buy a badge.
Endpoint
POST https://api.magentlab.com/api/calc/r_iss
| Category | Everything else |
|---|---|
| Provider host | api.magentlab.com |
| Networks | eip155:8453 |
| Payment schemes | exact |
| Self-reported calls, 30 days | 0 from 0 payers (the provider's figure, not ours) |
Our checks, last 30 days
| Day | Result | HTTP | Asked | Time |
|---|---|---|---|---|
| 2026-09-28 | valid payment request | 402 | $0.005 | 266 ms |
Example input (from the provider)
{
"body": {
"items": [
{
"albumin_g_dl": 4,
"albumin_g_l": 40,
"beta2_microglobulin_mg_l": 2,
"high_risk_ca": false,
"ldh_gt_uln": false
},
{
"albumin_g_dl": 4,
"albumin_g_l": 40,
"beta2_microglobulin_mg_l": 2,
"high_risk_ca": false,
"ldh_gt_uln": false
}
]
},
"method": "POST",
"type": "http"
}
Promised output schema (from the provider)
{
"$schema": "https://json-schema.org/draft/2020-12/schema",
"properties": {
"input": {
"additionalProperties": false,
"properties": {
"body": {
"additionalProperties": false,
"properties": {
"items": {
"items": {
"properties": {
"albumin_g_dl": {
"description": "Serum albumin in g/dL (1-6). Provide this or albumin_g_l, not both. ISS uses g/dL. Stage I requires albumin >= 3.5 when S\u03b22M < 3.5. Ignored when S\u03b22M >= 5.5.",
"type": "number"
},
"albumin_g_l": {
"description": "Serum albumin in g/L (10-60). Converted as g/dL = g/L / 10. Provide this or albumin_g_dl, not both.",
"type": "number"
},
"beta2_microglobulin_mg_l": {
"description": "Serum beta-2 microglobulin in mg/L (0.2-40). Greipp 2005 / Palumbo 2015 ISS. Stage I requires < 3.5; stage III when >= 5.5. magent does not assay beta-2 microglobulin.",
"type": "number"
},
"high_risk_ca": {
"description": "High-risk cytogenetic abnormalities as assigned by the caller: true iff del(17p) and/or t(4;14) and/or t(14;16) by iFISH (Palumbo 2015). magent does not FISH.",
"type": "boolean"
},
"ldh_gt_uln": {
"description": "Serum LDH greater than the upper limit of normal as assigned by the caller (Palumbo 2015: high LDH is > ULN). magent does not assay LDH or assign ULN.",
"type": "boolean"
}
},
"required": [
"beta2_microglobulin_mg_l",
"high_risk_ca",
"ldh_gt_uln"
],
"type": "object"
},
"maxItems": 25,
"minItems": 1,
"type": "array"
}
},
"required": [
"items"
],
"type": "object"
},
"headers": {
"additionalProperties": {
"type": "string"
},
"type": "object"
},
"method": {
"const": "POST",
"type": "string"
},
"type": {
"const": "http",
"type": "string"
}
},
"required": [
"type",
"method"
],
"type": "object"
},
"output": {
"properties": {
"example": {
"type": "object"
},
"type": {
"type": "string"
}
},
"required": [
"type"
],
"type": "object"
}
},
"required": [
"input"
],
"type": "object"
}