Lyon 2020 HFA-ICOS baseline CV risk before proteasome inhibitors and immunomodul
Lyon 2020 HFA-ICOS baseline CV risk before proteasome inhibitors and immunomodulatory drugs for multiple myeloma. Returns risk_level low, medium, high, or very_high plus medium_points and the paper's expert-opinion cardiotoxicity_guide. Age >=75 is High; 65-74 is Medium 1. Caller assigns labs, BMI >30, and high-dose dexamethasone. magent does not examine the patient or read imaging. Not a medical device or treatment order.
Asked 1.4x its listed price for its own exampleour last check, 2026-09-28
1 of 1checks answered this week
363 msmedian answer time
$0.005listed price per call
$0.007price it asked us
Paid test badge: not yet. The checks above are free: we call the tool without paying and read the payment request it sends back. The Verified badge needs paid calls whose answers match the promised output, and nobody can buy a badge.
Endpoint
POST https://api.magentlab.com/api/calc/hfa_icos_myeloma
| Category | Everything else |
|---|---|
| Provider host | api.magentlab.com |
| Networks | eip155:8453 |
| Payment schemes | exact |
| Self-reported calls, 30 days | 0 from 0 payers (the provider's figure, not ours) |
Our checks, last 30 days
| Day | Result | HTTP | Asked | Time |
|---|---|---|---|---|
| 2026-09-28 | valid payment request | 402 | $0.007 | 363 ms |
Example input (from the provider)
{
"body": {
"items": [
{
"age_years": 50,
"arrhythmia": false,
"arterial_vascular_disease": false,
"cardiac_amyloidosis": false,
"ckd": false,
"current_or_significant_smoker": false,
"diabetes": false,
"elevated_bnp": false,
"elevated_troponin": false,
"family_history_thrombophilia": false,
"heart_failure_or_cardiomyopathy": false,
"high_dose_dexamethasone": false,
"hyperlipidemia": false,
"hypertension": false,
"left_ventricular_hypertrophy": false,
"lvef_percent": 60,
"obesity": false,
"prior_anthracycline": false,
"prior_immunomodulatory_drug_cv_toxicity": false,
"prior_proteasome_inhibitor_cardiotoxicity": false,
"prior_thoracic_spine_radiotherapy": false,
"venous_thrombosis": false
},
{
"age_years": 50,
"arrhythmia": false,
"arterial_vascular_disease": false,
"cardiac_amyloidosis": false,
"ckd": false,
"current_or_significant_smoker": false,
"diabetes": false,
"elevated_bnp": false,
"elevated_troponin": false,
"family_history_thrombophilia": false,
"heart_failure_or_cardiomyopathy": false,
"high_dose_dexamethasone": false,
"hyperlipidemia": false,
"hypertension": false,
"left_ventricular_hypertrophy": false,
"lvef_percent": 60,
"obesity": false,
"prior_anthracycline": false,
"prior_immunomodulatory_drug_cv_toxicity": false,
"prior_proteasome_inhibitor_cardiotoxicity": false,
"prior_thoracic_spine_radiotherapy": false,
"venous_thrombosis": false
}
]
},
"method": "POST",
"type": "http"
}
Promised output schema (from the provider)
{
"$schema": "https://json-schema.org/draft/2020-12/schema",
"properties": {
"input": {
"additionalProperties": false,
"properties": {
"body": {
"additionalProperties": false,
"properties": {
"items": {
"items": {
"properties": {
"age_years": {
"description": "Age in years (18-100, integer). Lyon 2020 myeloma-therapy table: >=75 High; 65-74 Medium 1; <65 no age factor. Highest matching band only.",
"type": "integer"
},
"arrhythmia": {
"description": "Arrhythmia (Lyon 2020 Medium 2). true or false as assigned by the caller. magent does not read a rhythm strip.",
"type": "boolean"
},
"arterial_vascular_disease": {
"description": "Arterial vascular disease (IHD, PCI, CABG, stable angina, TIA, stroke, or PVD) as one caller bool (Lyon 2020 Very high). true or false. magent does not diagnose vascular disease.",
"type": "boolean"
},
"cardiac_amyloidosis": {
"description": "Cardiac amyloidosis (Lyon 2020 Very high). true or false as assigned by the caller. magent does not read imaging or biopsy.",
"type": "boolean"
},
"ckd": {
"description": "Chronic kidney disease as assigned by the caller (Lyon 2020 Medium 1). true or false. magent does not compute eGFR.",
"type": "boolean"
},
"current_or_significant_smoker": {
"description": "Current smoker or significant smoking history (Lyon 2020 Medium 1). true or false as assigned by the caller.",
"type": "boolean"
},
"diabetes": {
"description": "Diabetes mellitus as assigned by the caller (Lyon 2020 Medium 1). true or false. magent does not assay HbA1c.",
"type": "boolean"
},
"elevated_bnp": {
"description": "Baseline BNP or NT-proBNP above the local laboratory ULN as assigned by the caller (Lyon 2020 High). true or false. magent does not assay natriuretic peptides.",
"type": "boolean"
},
"elevated_troponin": {
"description": "Baseline troponin above the local laboratory ULN as assigned by the caller (Lyon 2020 Medium 2). true or false. magent does not assay troponin.",
"type": "boolean"
},
"family_history_thrombophilia": {
"description": "Family history of thrombophilia (Lyon 2020 Medium 1). true or false as assigned by the caller. magent does not take a family history.",
"type": "boolean"
},
"heart_failure_or_cardiomyopathy": {
"description": "Heart failure or cardiomyopathy (Lyon 2020 Very high). true or false as assigned by the caller. magent does not examine the patient or read imaging.",
"type": "boolean"
},
"high_dose_dexamethasone": {
"description": "High-dose dexamethasone (>160 mg/month) as assigned by the caller (Lyon 2020 Medium 1). true or false. magent does not compute a steroid dose.",
"type": "boolean"
},
"hyperlipidemia": {
"description": "Hyperlipidemia as assigned by the caller (Lyon 2020 Medium 1). true or false. magent does not assay lipids.",
"type": "boolean"
},
"hypertension": {
"description": "Hypertension as assigned by the caller (Lyon 2020 Medium 1). true or false. magent does not measure blood pressure.",
"type": "boolean"
},
"left_ventricular_hypertrophy": {
"description": "Left-ventricular hypertrophy (Lyon 2020 Medium 1). true or false as assigned by the caller. magent does not read imaging.",
"type": "boolean"
},
"lvef_percent": {
"description": "LVEF percent (10-80, integer). Lyon 2020: <50 High; 50-54 Medium 2; >=55 no LVEF factor. Highest matching printed band only. magent does not read imaging.",
"type": "integer"
},
"obesity": {
"description": "Obesity (BMI >30 kg/m2) as assigned by the caller (Lyon 2020 Medium 1). true or false. magent does not compute BMI.",
"type": "boolean"
},
"prior_anthracycline": {
"description": "Prior anthracycline exposure (Lyon 2020 High). true or false as assigned by the caller.",
"type": "boolean"
},
"prior_immunomodulatory_drug_cv_toxicity": {
"description": "Prior immunomodulatory-drug cardiovascular toxicity (Lyon 2020 High). true or false as assigned by the caller.",
"type": "boolean"
},
"prior_proteasome_inhibitor_cardiotoxicity": {
"description": "Prior proteasome-inhibitor cardiotoxicity (Lyon 2020 Very high). true or false as assigned by the caller.",
"type": "boolean"
},
"prior_thoracic_spine_radiotherapy": {
"description": "Prior thoracic-spine radiotherapy (Lyon 2020 Medium 1). true or false as assigned by the caller.",
"type": "boolean"
},
"venous_thrombosis": {
"description": "Venous