{"slug":"api-magentlab-com-api-calc-hfa-icos-myeloma-ed5e7b","title":"Lyon 2020 HFA-ICOS baseline CV risk before proteasome inhibitors and immunomodul","host":"api.magentlab.com","method":"POST","resource":"https://api.magentlab.com/api/calc/hfa_icos_myeloma","category":"other","description":"Lyon 2020 HFA-ICOS baseline CV risk before proteasome inhibitors and immunomodulatory drugs for multiple myeloma. Returns risk_level low, medium, high, or very_high plus medium_points and the paper's expert-opinion cardiotoxicity_guide. Age >=75 is High; 65-74 is Medium 1. Caller assigns labs, BMI >","price_listed":0.005,"price_asked":0.007,"state":"overcharges","state_label":"Asked 1.4x its listed price for its own example","checks_7d":1,"answered_7d":1,"latency_ms_median":363,"reported_calls_30d":0,"reported_payers_30d":0,"networks":["eip155:8453"],"badge":"unverified","paid_checks_7d":0,"paid_ok_7d":0,"example_input":{"body":{"items":[{"age_years":50,"arrhythmia":false,"arterial_vascular_disease":false,"cardiac_amyloidosis":false,"ckd":false,"current_or_significant_smoker":false,"diabetes":false,"elevated_bnp":false,"elevated_troponin":false,"family_history_thrombophilia":false,"heart_failure_or_cardiomyopathy":false,"high_dose_dexamethasone":false,"hyperlipidemia":false,"hypertension":false,"left_ventricular_hypertrophy":false,"lvef_percent":60,"obesity":false,"prior_anthracycline":false,"prior_immunomodulatory_drug_cv_toxicity":false,"prior_proteasome_inhibitor_cardiotoxicity":false,"prior_thoracic_spine_radiotherapy":false,"venous_thrombosis":false},{"age_years":50,"arrhythmia":false,"arterial_vascular_disease":false,"cardiac_amyloidosis":false,"ckd":false,"current_or_significant_smoker":false,"diabetes":false,"elevated_bnp":false,"elevated_troponin":false,"family_history_thrombophilia":false,"heart_failure_or_cardiomyopathy":false,"high_dose_dexamethasone":false,"hyperlipidemia":false,"hypertension":false,"left_ventricular_hypertrophy":false,"lvef_percent":60,"obesity":false,"prior_anthracycline":false,"prior_immunomodulatory_drug_cv_toxicity":false,"prior_proteasome_inhibitor_cardiotoxicity":false,"prior_thoracic_spine_radiotherapy":false,"venous_thrombosis":false}]},"method":"POST","type":"http"},"output_schema":{"$schema":"https://json-schema.org/draft/2020-12/schema","properties":{"input":{"additionalProperties":false,"properties":{"body":{"additionalProperties":false,"properties":{"items":{"items":{"properties":{"age_years":{"description":"Age in years (18-100, integer). Lyon 2020 myeloma-therapy table: >=75 High; 65-74 Medium 1; <65 no age factor. Highest matching band only.","type":"integer"},"arrhythmia":{"description":"Arrhythmia (Lyon 2020 Medium 2). true or false as assigned by the caller. magent does not read a rhythm strip.","type":"boolean"},"arterial_vascular_disease":{"description":"Arterial vascular disease (IHD, PCI, CABG, stable angina, TIA, stroke, or PVD) as one caller bool (Lyon 2020 Very high). true or false. magent does not diagnose vascular disease.","type":"boolean"},"cardiac_amyloidosis":{"description":"Cardiac amyloidosis (Lyon 2020 Very high). true or false as assigned by the caller. magent does not read imaging or biopsy.","type":"boolean"},"ckd":{"description":"Chronic kidney disease as assigned by the caller (Lyon 2020 Medium 1). true or false. magent does not compute eGFR.","type":"boolean"},"current_or_significant_smoker":{"description":"Current smoker or significant smoking history (Lyon 2020 Medium 1). true or false as assigned by the caller.","type":"boolean"},"diabetes":{"description":"Diabetes mellitus as assigned by the caller (Lyon 2020 Medium 1). true or false. magent does not assay HbA1c.","type":"boolean"},"elevated_bnp":{"description":"Baseline BNP or NT-proBNP above the local laboratory ULN as assigned by the caller (Lyon 2020 High). true or false. magent does not assay natriuretic peptides.","type":"boolean"},"elevated_troponin":{"description":"Baseline troponin above the local laboratory ULN as assigned by the caller (Lyon 2020 Medium 2). true or false. magent does not assay troponin.","type":"boolean"},"family_history_thrombophilia":{"description":"Family history of thrombophilia (Lyon 2020 Medium 1). true or false as assigned by the caller. magent does not take a family history.","type":"boolean"},"heart_failure_or_cardiomyopathy":{"description":"Heart failure or cardiomyopathy (Lyon 2020 Very high). true or false as assigned by the caller. magent does not examine the patient or read imaging.","type":"boolean"},"high_dose_dexamethasone":{"description":"High-dose dexamethasone (>160 mg/month) as assigned by the caller (Lyon 2020 Medium 1). true or false. magent does not compute a steroid dose.","type":"boolean"},"hyperlipidemia":{"description":"Hyperlipidemia as assigned by the caller (Lyon 2020 Medium 1). true or false. magent does not assay lipids.","type":"boolean"},"hypertension":{"description":"Hypertension as assigned by the caller (Lyon 2020 Medium 1). true or false. magent does not measure blood pressure.","type":"boolean"},"left_ventricular_hypertrophy":{"description":"Left-ventricular hypertrophy (Lyon 2020 Medium 1). true or false as assigned by the caller. magent does not read imaging.","type":"boolean"},"lvef_percent":{"description":"LVEF percent (10-80, integer). Lyon 2020: <50 High; 50-54 Medium 2; >=55 no LVEF factor. Highest matching printed band only. magent does not read imaging.","type":"integer"},"obesity":{"description":"Obesity (BMI >30 kg/m2) as assigned by the caller (Lyon 2020 Medium 1). true or false. magent does not compute BMI.","type":"boolean"},"prior_anthracycline":{"description":"Prior anthracycline exposure (Lyon 2020 High). true or false as assigned by the caller.","type":"boolean"},"prior_immunomodulatory_drug_cv_toxicity":{"description":"Prior immunomodulatory-drug cardiovascular toxicity (Lyon 2020 High). true or false as assigned by the caller.","type":"boolean"},"prior_proteasome_inhibitor_cardiotoxicity":{"description":"Prior proteasome-inhibitor cardiotoxicity (Lyon 2020 Very high). true or false as assigned by the caller.","type":"boolean"},"prior_thoracic_spine_radiotherapy":{"description":"Prior thoracic-spine radiotherapy (Lyon 2020 Medium 1). true or false as assigned by the caller.","type":"boolean"},"venous_thrombosis":{"description":"Venous thrombosis (DVT or PE) (Lyon 2020 Very high). true or false as assigned by the caller. magent does not diagnose thrombosis.","type":"boolean"}},"required":["age_years","lvef_percent","heart_failure_or_cardiomyopathy","prior_proteasome_inhibitor_cardiotoxicity","venous_thrombosis","cardiac_amyloidosis","arterial_vascular_disease","prior_immunomodulatory_drug_cv_toxicity","elevated_bnp","prior_anthracycline","arrhythmia","elevated_troponin","left_ventricular_hypertrophy","hypertension","diabetes","hyperlipidemia","ckd","family_history_thrombophilia","prior_thoracic_spine_radiotherapy","high_dose_dexamethasone","current_or_significant_smoker","obesity"],"type":"object"},"maxItems":25,"minItems":1,"type":"array"}},"required":["items"],"type":"object"},"headers":{"additionalProperties":{"type":"string"},"type":"object"},"method":{"const":"POST","type":"string"},"type":{"const":"http","type":"string"}},"required":["type","method"],"type":"object"},"output":{"properties":{"example":{"type":"object"},"type":{"type":"string"}},"required":["type"],"type":"object"}},"required":["input"],"type":"object"},"history":[{"day":"2026-09-28","reachable":true,"status":402,"valid_402":true,"asked_usdc":0.007,"price_match":false,"latency_ms":363,"error":null}],"description_full":"Lyon 2020 HFA-ICOS baseline CV risk before proteasome inhibitors and immunomodulatory drugs for multiple myeloma. Returns risk_level low, medium, high, or very_high plus medium_points and the paper's expert-opinion cardiotoxicity_guide. Age >=75 is High; 65-74 is Medium 1. Caller assigns labs, BMI >30, and high-dose dexamethasone. magent does not examine the patient or read imaging. Not a medical device or treatment order.","last_updated":"2026-09-28T13:45:43.417Z","schemes":["exact"]}