Ranzani 2025 SOFA-2 from six organs 0-4 (brain, respiratory, cardiovascular, liv

Ranzani 2025 SOFA-2 from six organs 0-4 (brain, respiratory, cardiovascular, liver, kidney, hemostasis), max 24. Maps PaO2/FiO2 or SpO2/FiO2 with NIV/ECMO, MAP and vasopressor dose bands, caller-assigned GCS and delirium-drug flag, bilirubin, platelets, creatinine or urine rate, and RRT. Not Vincent 1996 SOFA and not a diagnosis.

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Endpoint

POST https://api.magentlab.com/api/calc/sofa_2

Our checks, last 30 days

Example input (from the provider)

{
  "body": {
    "items": [
      {
        "advanced_ventilatory_support": false,
        "bilirubin_mg_dl": 0.8,
        "bilirubin_umol_l": 13.7,
        "creatinine_mg_dl": 1,
        "creatinine_umol_l": 88,
        "delirium_drugs": false,
        "dopamine_ug_kg_min": 0,
        "ecmo": false,
        "epinephrine_ug_kg_min": 0,
        "fio2": 0.21,
        "gcs": 15,
        "map_mm_hg": 80,
        "mechanical_circulatory_support": false,
        "norepinephrine_ug_kg_min": 0,
        "oliguria_hours": 8,
        "other_vasopressor_or_inotrope": false,
        "pao2_mm_hg": 96,
        "platelets_10e9_l": 200,
        "rrt": false,
        "spo2": 96,
        "urine_output_ml_kg_h": 1,
        "vasoactive_unavailable": false,
        "ventilatory_support_unavailable": false
      },
      {
        "advanced_ventilatory_support": false,
        "bilirubin_mg_dl": 0.8,
        "bilirubin_umol_l": 13.7,
        "creatinine_mg_dl": 1,
        "creatinine_umol_l": 88,
        "delirium_drugs": false,
        "dopamine_ug_kg_min": 0,
        "ecmo": false,
        "epinephrine_ug_kg_min": 0,
        "fio2": 0.21,
        "gcs": 15,
        "map_mm_hg": 80,
        "mechanical_circulatory_support": false,
        "norepinephrine_ug_kg_min": 0,
        "oliguria_hours": 8,
        "other_vasopressor_or_inotrope": false,
        "pao2_mm_hg": 96,
        "platelets_10e9_l": 200,
        "rrt": false,
        "spo2": 96,
        "urine_output_ml_kg_h": 1,
        "vasoactive_unavailable": false,
        "ventilatory_support_unavailable": false
      }
    ]
  },
  "method": "POST",
  "type": "http"
}

Promised output schema (from the provider)

{
  "$schema": "https://json-schema.org/draft/2020-12/schema",
  "properties": {
    "input": {
      "additionalProperties": false,
      "properties": {
        "body": {
          "additionalProperties": false,
          "properties": {
            "items": {
              "items": {
                "properties": {
                  "advanced_ventilatory_support": {
                    "description": "High-flow nasal cannula, CPAP, bilevel positive airway pressure, noninvasive ventilation, invasive mechanical ventilation, or long-term home ventilation (Ranzani 2025). true or false. Respiratory scores 3 and 4 require this, ventilatory_support_unavailable, or respiratory ECMO.",
                    "type": "boolean"
                  },
                  "bilirubin_mg_dl": {
                    "description": "Total bilirubin in mg/dL (0.1-40). Provide this or bilirubin_umol_l. \u22641.20 scores 0; \u22643.0 scores 1; \u22646.0 scores 2; \u226412.0 scores 3; >12.0 scores 4.",
                    "type": "number"
                  },
                  "bilirubin_umol_l": {
                    "description": "Total bilirubin in \u00b5mol/L (2-684). \u226420.6 scores 0; \u226451.3 scores 1; \u2264102.6 scores 2; \u2264205 scores 3; >205 scores 4.",
                    "type": "number"
                  },
                  "creatinine_mg_dl": {
                    "description": "Creatinine in mg/dL (0.1-20). Provide this, creatinine_umol_l, or rrt=true. \u22641.20 scores 0; \u22642.0 scores 1; \u22643.50 scores 2; >3.50 scores 3. Kidney is the max of creatinine, urine, and RRT.",
                    "type": "number"
                  },
                  "creatinine_umol_l": {
                    "description": "Creatinine in \u00b5mol/L (9-1768). \u2264110 scores 0; \u2264170 scores 1; \u2264300 scores 2; >300 scores 3.",
                    "type": "number"
                  },
                  "delirium_drugs": {
                    "description": "Drugs given to treat delirium (Ranzani 2025). true or false when provided; absent is false. true scores brain at least 1 even if GCS is 15.",
                    "type": "boolean"
                  },
                  "dopamine_ug_kg_min": {
                    "description": "Dopamine in \u00b5g/kg\u00b7min (0-80) when provided. Absent is 0. As a single vasopressor: \u226420 scores 2; >20 to 40 scores 3; >40 scores 4. With norepinephrine, epinephrine, or another agent it counts as an other vasopressor or inotrope.",
                    "type": "number"
                  },
                  "ecmo": {
                    "description": "Respiratory ECMO of any form. true or false when provided; absent is false. true scores respiratory 4 regardless of PaO2/FiO2 or SpO2/FiO2 and does not by itself score cardiovascular points.",
                    "type": "boolean"
                  },
                  "epinephrine_ug_kg_min": {
                    "description": "Epinephrine in \u00b5g/kg\u00b7min (0-10) when provided. Absent is 0. Added to norepinephrine for the published dose bands.",
                    "type": "number"
                  },
                  "fio2": {
                    "description": "Inspired oxygen as a fraction (0.21-1.0), not a percent.",
                    "type": "number"
                  },
                  "gcs": {
                    "description": "Glasgow Coma Scale total as assigned by the caller (integer 3-15), including last pre-sedation GCS or the motor scale when the three-domain GCS cannot be evaluated. 15 scores 0; 13-14 scores 1; 9-12 scores 2; 6-8 scores 3; 3-5 scores 4. magent does not examine the patient.",
                    "type": "integer"
                  },
                  "map_mm_hg": {
                    "description": "Mean arterial pressure in mm Hg (20-180). MAP <70 with no vasopressor or inotrope scores 1 unless a higher cardiovascular band applies. When vasoactive_unavailable is true, MAP \u226570 scores 0; 60-69 scores 1; 50-59 scores 2; 40-49 scores 3; <40 scores 4.",
                    "type": "number"
                  },
                  "mechanical_circulatory_support": {
                    "description": "Mechanical circulatory support (veno-arterial ECMO, intra-aortic balloon pump, left ventricular assist device, or microaxial flow pump). true or false when provided; absent is false. true scores cardiovascular 4.",
                    "type": "boolean"
                  },
                  "norepinephrine_ug_kg_min": {
                    "description": "Norepinephrine as the base in \u00b5g/kg\u00b7min (0-10) when provided. Absent is 0. Summed with epinephrine: >0 to \u22640.2 scores 2; >0.2 to \u22640.4 scores 3; >0.4 scores 4. Low-dose plus any other vasopressor or inotrope scores 3; medium-dose plus any other, or mechanical circulatory support, scores 4.",
                    "type": "number"
                  },
                  "oliguria_hours": {
                    "description": "Hours at the reported urine_output_ml_kg_h (0-72). Required when urine_output_ml_kg_h is provided.",
                    "type": "number"
                  },
                  "other_vasopressor_or_inotrope": {
                    "description": "Any other vasopressor or inotrope (Ranzani 2025). true or false when provided; absent is false. Any dose scores cardiovascular 2 unless a higher norepinephrine/epinephrine or mechanical band applies.",
                    "type": "boolean"
                  },
                  "pao2_mm_hg": {
                    "description": "Arterial PaO2 in mm Hg (20-700). Provide this with fio2, or spo2 with fio2 when PaO2 is unavailable. PaO2/FiO2 >300 scores 0; \u2264300 scores 1; \u2264225 scores 2; \u2264150 with advanced ventilatory support scores 3; \u226475 with advanced ventilatory support scores 4. Respiratory ECMO scores 4 regardless of the ratio.",
                    "type": "number"
                  },
                  "platelets_1

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