Álvarez-Twose 2012 REMA
Álvarez-Twose 2012 REMA: male +1, female −1; serum baseline tryptase <15 μg/L −1, 15–25 0, >25 +2; pruritus, hives or angioedema present −2, absent +1; syncope or presyncope +3. Range −4 to +7. Clonality likely iff score ≥2. Caller assigns sex, sBt, cutaneous signs, and syncope. Not a medical device, not a diagnosis of SM, not WHO SM criteria. magent does not assay tryptase.
Asked 1.4x its listed price for its own exampleour last check, 2026-09-28
1 of 1checks answered this week
279 msmedian answer time
$0.005listed price per call
$0.007price it asked us
Paid test badge: not yet. The checks above are free: we call the tool without paying and read the payment request it sends back. The Verified badge needs paid calls whose answers match the promised output, and nobody can buy a badge.
Endpoint
POST https://api.magentlab.com/api/calc/rema
| Category | Everything else |
|---|---|
| Provider host | api.magentlab.com |
| Networks | eip155:8453 |
| Payment schemes | exact |
| Self-reported calls, 30 days | 0 from 0 payers (the provider's figure, not ours) |
Our checks, last 30 days
| Day | Result | HTTP | Asked | Time |
|---|---|---|---|---|
| 2026-09-28 | valid payment request | 402 | $0.007 | 279 ms |
Example input (from the provider)
{
"body": {
"items": [
{
"pruritus_hives_angioedema": false,
"sex": "male",
"syncope_or_presyncope": true,
"tryptase_ug_l": 30
},
{
"pruritus_hives_angioedema": false,
"sex": "male",
"syncope_or_presyncope": true,
"tryptase_ug_l": 30
}
]
},
"method": "POST",
"type": "http"
}
Promised output schema (from the provider)
{
"$schema": "https://json-schema.org/draft/2020-12/schema",
"properties": {
"input": {
"additionalProperties": false,
"properties": {
"body": {
"additionalProperties": false,
"properties": {
"items": {
"items": {
"properties": {
"pruritus_hives_angioedema": {
"description": "Presence of pruritus, hives or angioedema as assigned by the caller (\u00c1lvarez-Twose 2012). true scores \u22122; false (absence) scores +1. Both branches score. magent does not take a history.",
"type": "boolean"
},
"sex": {
"description": "Sex as assigned by the caller (\u00c1lvarez-Twose 2012). male scores +1; female scores \u22121. Always one of these.",
"enum": [
"female",
"male"
],
"type": "string"
},
"syncope_or_presyncope": {
"description": "Syncope or presyncope as assigned by the caller (\u00c1lvarez-Twose 2012). true scores +3; false scores 0.",
"type": "boolean"
},
"tryptase_ug_l": {
"description": "Serum baseline tryptase (sBt) in \u03bcg/L (1-200). <15 scores \u22121; 15\u201325 inclusive scores 0; >25 scores +2. Equal to 15 is not <15; equal to 25 is not >25. magent does not assay tryptase.",
"type": "number"
}
},
"required": [
"sex",
"tryptase_ug_l",
"pruritus_hives_angioedema",
"syncope_or_presyncope"
],
"type": "object"
},
"maxItems": 25,
"minItems": 1,
"type": "array"
}
},
"required": [
"items"
],
"type": "object"
},
"headers": {
"additionalProperties": {
"type": "string"
},
"type": "object"
},
"method": {
"const": "POST",
"type": "string"
},
"type": {
"const": "http",
"type": "string"
}
},
"required": [
"type",
"method"
],
"type": "object"
},
"output": {
"properties": {
"example": {
"type": "object"
},
"type": {
"type": "string"
}
},
"required": [
"type"
],
"type": "object"
}
},
"required": [
"input"
],
"type": "object"
}