Jawhar 2019 mutation-adjusted risk score (MARS) for advanced systemic mastocytos
Jawhar 2019 mutation-adjusted risk score (MARS) for advanced systemic mastocytosis: age >60 (1), hemoglobin <10 g/dL (1), platelets <100×10^9/L (1), exactly one S/A/R mutation among SRSF2, ASXL1, RUNX1 (1) or two or more (2, not both). Max 5. Low 0–1 (training-set median OS not reached), intermediate 2 (3.9 y), high 3–5 (1.9 y). Not WHO SM criteria. magent does not sequence or assay labs.
Answeringour last check, 2026-09-28
1 of 1checks answered this week
240 msmedian answer time
$0.005listed price per call
$0.005price it asked us
Paid test badge: not yet. The checks above are free: we call the tool without paying and read the payment request it sends back. The Verified badge needs paid calls whose answers match the promised output, and nobody can buy a badge.
Endpoint
POST https://api.magentlab.com/api/calc/mars
| Category | Everything else |
|---|---|
| Provider host | api.magentlab.com |
| Networks | eip155:8453 |
| Payment schemes | exact |
| Self-reported calls, 30 days | 0 from 0 payers (the provider's figure, not ours) |
Our checks, last 30 days
| Day | Result | HTTP | Asked | Time |
|---|---|---|---|---|
| 2026-09-28 | valid payment request | 402 | $0.005 | 240 ms |
Example input (from the provider)
{
"body": {
"items": [
{
"age": 50,
"hemoglobin_g_dl": 12,
"hemoglobin_g_l": 120,
"platelets_10e9_l": 200,
"sar_mutation_count": 0
},
{
"age": 50,
"hemoglobin_g_dl": 12,
"hemoglobin_g_l": 120,
"platelets_10e9_l": 200,
"sar_mutation_count": 0
}
]
},
"method": "POST",
"type": "http"
}
Promised output schema (from the provider)
{
"$schema": "https://json-schema.org/draft/2020-12/schema",
"properties": {
"input": {
"additionalProperties": false,
"properties": {
"body": {
"additionalProperties": false,
"properties": {
"items": {
"items": {
"properties": {
"age": {
"description": "Age in years (integer 18-120). >60 scores 1 (Jawhar 2019). Age 61 scores; age 60 is the \u226460 arm and scores 0.",
"type": "integer"
},
"hemoglobin_g_dl": {
"description": "Hemoglobin in g/dL (3-22). Provide this or hemoglobin_g_l, not both. <10 g/dL (<100 g/L) scores 1 (Jawhar 2019). 10.0 is the \u226510 arm and scores 0. magent does not assay hemoglobin.",
"type": "number"
},
"hemoglobin_g_l": {
"description": "Hemoglobin in g/L (30-220). Converted as hemoglobin_g_dl = hemoglobin_g_l / 10. Provide this or hemoglobin_g_dl, not both. <100 g/L scores 1. 100 is the \u2265100 arm and scores 0.",
"type": "number"
},
"platelets_10e9_l": {
"description": "Platelet count in 10^9/L (1-2000). <100 scores 1 (Jawhar 2019). 100.0 is the \u2265100 arm and scores 0. magent does not assay platelets.",
"type": "number"
},
"sar_mutation_count": {
"description": "Caller-assigned count of S/A/R mutations among SRSF2, ASXL1, and RUNX1 (integer 0, 1, or 2; 2 means two or more). Exactly one scores 1. Two or more scores 2 (not 1 plus 2). Count 0 scores 0. magent does not sequence.",
"type": "integer"
}
},
"required": [
"age",
"platelets_10e9_l",
"sar_mutation_count"
],
"type": "object"
},
"maxItems": 25,
"minItems": 1,
"type": "array"
}
},
"required": [
"items"
],
"type": "object"
},
"headers": {
"additionalProperties": {
"type": "string"
},
"type": "object"
},
"method": {
"const": "POST",
"type": "string"
},
"type": {
"const": "http",
"type": "string"
}
},
"required": [
"type",
"method"
],
"type": "object"
},
"output": {
"properties": {
"example": {
"type": "object"
},
"type": {
"type": "string"
}
},
"required": [
"type"
],
"type": "object"
}
},
"required": [
"input"
],
"type": "object"
}