Khorana 2008 Blood predictive model for chemotherapy-associated thrombosis

Khorana 2008 Blood predictive model for chemotherapy-associated thrombosis: very_high site (stomach or pancreas) 2, high (lung, lymphoma, gynecologic, bladder, testicular) 1, other 0; platelets >=350 1; hemoglobin <10 g/dL or ESA 1 (once); WBC >11 x10^9/L 1; BMI>=35 caller flag 1. Max 6. 0 low; 1-2 intermediate; >=3 high. Not a diagnosis. Not Padua or Caprini. Caller assigns cancer site; magent does not compute BMI.

Paid test badge: not yet. The checks above are free: we call the tool without paying and read the payment request it sends back. The Verified badge needs paid calls whose answers match the promised output, and nobody can buy a badge.

Endpoint

POST https://api.magentlab.com/api/calc/khorana

Our checks, last 30 days

Example input (from the provider)

{
  "body": {
    "items": [
      {
        "bmi_ge_35": false,
        "cancer_site": "other",
        "erythropoiesis_stimulating_agent": false,
        "hemoglobin_g_dl": 12,
        "hemoglobin_g_l": 120,
        "platelets_10e9_l": 200,
        "wbc_k_ul": 8,
        "wbc_ul": 8000
      },
      {
        "bmi_ge_35": false,
        "cancer_site": "other",
        "erythropoiesis_stimulating_agent": false,
        "hemoglobin_g_dl": 12,
        "hemoglobin_g_l": 120,
        "platelets_10e9_l": 200,
        "wbc_k_ul": 8,
        "wbc_ul": 8000
      }
    ]
  },
  "method": "POST",
  "type": "http"
}

Promised output schema (from the provider)

{
  "$schema": "https://json-schema.org/draft/2020-12/schema",
  "properties": {
    "input": {
      "additionalProperties": false,
      "properties": {
        "body": {
          "additionalProperties": false,
          "properties": {
            "items": {
              "items": {
                "properties": {
                  "bmi_ge_35": {
                    "description": "BMI \u226535 as assigned by the caller. true or false. magent does not take height or weight. 1 point if true.",
                    "type": "boolean"
                  },
                  "cancer_site": {
                    "description": "Caller-assigned Khorana site class. very_high (stomach or pancreas) scores 2; high (lung, lymphoma, gynecologic, bladder, or testicular) scores 1; other scores 0. magent does not assign cancer site from histology text.",
                    "type": "string"
                  },
                  "erythropoiesis_stimulating_agent": {
                    "description": "Use of an erythropoiesis-stimulating agent as assigned by the caller. true or false. Scores 1 with hemoglobin <10 g/dL (once, not twice).",
                    "type": "boolean"
                  },
                  "hemoglobin_g_dl": {
                    "description": "Hemoglobin in g/dL (3-22). Provide this or hemoglobin_g_l, not both. <10 scores 1 with ESA (once, not twice). 10.0 does not score unless ESA is true.",
                    "type": "number"
                  },
                  "hemoglobin_g_l": {
                    "description": "Hemoglobin in g/L (30-220). Converted as hemoglobin_g_dl = hemoglobin_g_l / 10. Provide this or hemoglobin_g_dl, not both.",
                    "type": "number"
                  },
                  "platelets_10e9_l": {
                    "description": "Pre-chemotherapy platelet count \u00d710^9/L (1-2000). \u2265350 scores 1 (350 scores; 349 does not).",
                    "type": "number"
                  },
                  "wbc_k_ul": {
                    "description": "WBC in 10^3/\u00b5L (same as 10^9/L). Provide wbc_k_ul or wbc_ul. Range 0.01-500. >11 scores 1 (11.0 does not).",
                    "type": "number"
                  },
                  "wbc_ul": {
                    "description": "WBC in cells/\u00b5L (same as cells/mm^3). Provide wbc_k_ul or wbc_ul. Range 10-500000. >11000 scores 1 (11000 does not).",
                    "type": "number"
                  }
                },
                "required": [
                  "cancer_site",
                  "platelets_10e9_l",
                  "erythropoiesis_stimulating_agent",
                  "bmi_ge_35"
                ],
                "type": "object"
              },
              "maxItems": 25,
              "minItems": 1,
              "type": "array"
            }
          },
          "required": [
            "items"
          ],
          "type": "object"
        },
        "headers": {
          "additionalProperties": {
            "type": "string"
          },
          "type": "object"
        },
        "method": {
          "const": "POST",
          "type": "string"
        },
        "type": {
          "const": "http",
          "type": "string"
        }
      },
      "required": [
        "type",
        "method"
      ],
      "type": "object"
    },
    "output": {
      "properties": {
        "example": {
          "type": "object"
        },
        "type": {
          "type": "string"
        }
      },
      "required": [
        "type"
      ],
      "type": "object"
    }
  },
  "required": [
    "input"
  ],
  "type": "object"
}

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