Dubois 2014 IWG-2 typical AD research criteria
Dubois 2014 IWG-2 typical AD research criteria. typical_ad iff early hippocampal-type episodic memory, no better explanation, and in-vivo AD pathology (CSF Abeta1-42 plus T-tau or P-tau, amyloid PET, or a PSEN1/PSEN2/APP mutation). Typical AD only; not atypical phenotypes. Not NINCDS-ADRDA, not NIA-AA ATN, not DSM. magent does not examine the patient, assay CSF, or read PET. Not a diagnosis or medical device.
Asked 1.4x its listed price for its own exampleour last check, 2026-09-28
1 of 1checks answered this week
308 msmedian answer time
$0.005listed price per call
$0.007price it asked us
Paid test badge: not yet. The checks above are free: we call the tool without paying and read the payment request it sends back. The Verified badge needs paid calls whose answers match the promised output, and nobody can buy a badge.
Endpoint
POST https://api.magentlab.com/api/calc/iwg2_ad
| Category | Search and research |
|---|---|
| Provider host | api.magentlab.com |
| Networks | eip155:8453 |
| Payment schemes | exact |
| Self-reported calls, 30 days | 0 from 0 payers (the provider's figure, not ours) |
Our checks, last 30 days
| Day | Result | HTTP | Asked | Time |
|---|---|---|---|---|
| 2026-09-28 | valid payment request | 402 | $0.007 | 308 ms |
Example input (from the provider)
{
"body": {
"items": [
{
"amyloid_pet": false,
"autosomal_dominant_mutation": false,
"csf_abeta_and_tau": true,
"early_episodic_memory": true,
"no_better_explanation": true
},
{
"amyloid_pet": false,
"autosomal_dominant_mutation": false,
"csf_abeta_and_tau": true,
"early_episodic_memory": true,
"no_better_explanation": true
}
]
},
"method": "POST",
"type": "http"
}
Promised output schema (from the provider)
{
"$schema": "https://json-schema.org/draft/2020-12/schema",
"properties": {
"input": {
"additionalProperties": false,
"properties": {
"body": {
"additionalProperties": false,
"properties": {
"items": {
"items": {
"properties": {
"amyloid_pet": {
"description": "Increased tracer retention on amyloid PET, as assigned by the caller (Dubois 2014 IWG-2 in-vivo AD pathology). true or false. magent does not read PET.",
"type": "boolean"
},
"autosomal_dominant_mutation": {
"description": "Proven AD autosomal-dominant mutation in PSEN1, PSEN2, or APP, as assigned by the caller (Dubois 2014 IWG-2 in-vivo AD pathology). true or false. magent does not sequence genes.",
"type": "boolean"
},
"csf_abeta_and_tau": {
"description": "Decreased A\u03b21-42 together with increased T-tau or P-tau in CSF, as assigned by the caller (Dubois 2014 IWG-2 in-vivo AD pathology). true or false. magent does not assay CSF.",
"type": "boolean"
},
"early_episodic_memory": {
"description": "Early and significant episodic memory impairment of the hippocampal type (IWG-2 specific phenotype for typical AD), as assigned by the caller. true or false. magent does not examine the patient.",
"type": "boolean"
},
"no_better_explanation": {
"description": "Exclusion of other disorders that could account for the phenotype, as assigned by the caller (Dubois 2014 IWG-2). true or false. magent does not examine the patient.",
"type": "boolean"
}
},
"required": [
"early_episodic_memory",
"csf_abeta_and_tau",
"amyloid_pet",
"autosomal_dominant_mutation",
"no_better_explanation"
],
"type": "object"
},
"maxItems": 25,
"minItems": 1,
"type": "array"
}
},
"required": [
"items"
],
"type": "object"
},
"headers": {
"additionalProperties": {
"type": "string"
},
"type": "object"
},
"method": {
"const": "POST",
"type": "string"
},
"type": {
"const": "http",
"type": "string"
}
},
"required": [
"type",
"method"
],
"type": "object"
},
"output": {
"properties": {
"example": {
"type": "object"
},
"type": {
"type": "string"
}
},
"required": [
"type"
],
"type": "object"
}
},
"required": [
"input"
],
"type": "object"
}