Brahmer 2018 ASCO Table 3.1 irAE pneumonitis

Brahmer 2018 ASCO Table 3.1 irAE pneumonitis. First-match: G4 life-threatening respiratory compromise; else G3 hospitalization, oxygen, limiting self-care, or all lobes/>50%; else G2 symptomatic, >1 lobe, 25-50% parenchyma, or limiting instrumental ADL; else G1. ICPi: hold_if_radiographic_progression (G1), hold (G2), permanently_discontinue (G3-4). Caller-assigned flags. magent does not read CT or pulse oximetry. Not SITC 2021, not a CTCAE instrument, not a diagnosis, not a steroid dose.

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Endpoint

POST https://api.magentlab.com/api/calc/irae_pneumonitis

Our checks, last 30 days

Example input (from the provider)

{
  "body": {
    "items": [
      {
        "all_lobes_or_gt_50_pct": false,
        "extent_25_to_50_pct": false,
        "hospitalization_required": false,
        "life_threatening_respiratory": false,
        "limiting_instrumental_adl": false,
        "limiting_self_care": false,
        "more_than_one_lobe": false,
        "oxygen_indicated": false,
        "symptomatic": false
      },
      {
        "all_lobes_or_gt_50_pct": false,
        "extent_25_to_50_pct": false,
        "hospitalization_required": false,
        "life_threatening_respiratory": false,
        "limiting_instrumental_adl": false,
        "limiting_self_care": false,
        "more_than_one_lobe": false,
        "oxygen_indicated": false,
        "symptomatic": false
      }
    ]
  },
  "method": "POST",
  "type": "http"
}

Promised output schema (from the provider)

{
  "$schema": "https://json-schema.org/draft/2020-12/schema",
  "properties": {
    "input": {
      "additionalProperties": false,
      "properties": {
        "body": {
          "additionalProperties": false,
          "properties": {
            "items": {
              "items": {
                "properties": {
                  "all_lobes_or_gt_50_pct": {
                    "description": "Involves all lung lobes or >50% of lung parenchyma as assigned by the caller (Brahmer 2018 Table 3.1 grade 3). true or false. magent does not read CT.",
                    "type": "boolean"
                  },
                  "extent_25_to_50_pct": {
                    "description": "Involves 25%\u201350% of lung parenchyma as assigned by the caller (Brahmer 2018 Table 3.1 grade 2). true or false. magent does not read CT.",
                    "type": "boolean"
                  },
                  "hospitalization_required": {
                    "description": "Hospitalization required as assigned by the caller (Brahmer 2018 Table 3.1 grade 3). true or false. magent does not decide admission.",
                    "type": "boolean"
                  },
                  "life_threatening_respiratory": {
                    "description": "Life-threatening respiratory compromise with urgent intervention indicated (intubation) as assigned by the caller (Brahmer 2018 Table 3.1 grade 4). true or false. When true, grade is 4 regardless of other flags. magent does not examine the patient or set a ventilator.",
                    "type": "boolean"
                  },
                  "limiting_instrumental_adl": {
                    "description": "Limiting instrumental ADL as assigned by the caller (Brahmer 2018 Table 3.1 grade 2). true or false. magent does not assess ADL.",
                    "type": "boolean"
                  },
                  "limiting_self_care": {
                    "description": "Limiting self-care ADL as assigned by the caller (Brahmer 2018 Table 3.1 grade 3). true or false. magent does not assess ADL.",
                    "type": "boolean"
                  },
                  "more_than_one_lobe": {
                    "description": "Involves more than one lobe as assigned by the caller (Brahmer 2018 Table 3.1 grade 2). true or false. magent does not read CT.",
                    "type": "boolean"
                  },
                  "oxygen_indicated": {
                    "description": "Oxygen indicated as assigned by the caller (Brahmer 2018 Table 3.1 grade 3). true or false. magent does not read pulse oximetry or start oxygen.",
                    "type": "boolean"
                  },
                  "symptomatic": {
                    "description": "Symptomatic as assigned by the caller (Brahmer 2018 Table 3.1 grade 2). true or false. magent does not examine the patient.",
                    "type": "boolean"
                  }
                },
                "required": [
                  "life_threatening_respiratory",
                  "hospitalization_required",
                  "oxygen_indicated",
                  "limiting_self_care",
                  "all_lobes_or_gt_50_pct",
                  "symptomatic",
                  "more_than_one_lobe",
                  "extent_25_to_50_pct",
                  "limiting_instrumental_adl"
                ],
                "type": "object"
              },
              "maxItems": 25,
              "minItems": 1,
              "type": "array"
            }
          },
          "required": [
            "items"
          ],
          "type": "object"
        },
        "headers": {
          "additionalProperties": {
            "type": "string"
          },
          "type": "object"
        },
        "method": {
          "const": "POST",
          "type": "string"
        },
        "type": {
          "const": "http",
          "type": "string"
        }
      },
      "required": [
        "type",
        "method"
      ],
      "type": "object"
    },
    "output": {
      "properties": {
        "example": {
          "type": "object"
        },
        "type": {
          "type": "string"
        }
      },
      "required": [
        "type"
      ],
      "type": "object"
    }
  },
  "required": [
    "input"
  ],
  "type": "object"
}

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