Brahmer 2018 ASCO Table 4.1.1 irAE primary hypothyroidism grade from tsh_miu_l (
Brahmer 2018 ASCO Table 4.1.1 irAE primary hypothyroidism grade from tsh_miu_l (0.01-150 mIU/L) and three caller-assigned flags. First-match: grade 3 if severe_or_life_threatening or unable_to_perform_adl (paper G3-4 as grade 3); else 2 if moderate_symptoms or TSH >= 10; else 1 if TSH < 10. Returns icpi_action continue (grade 1) or hold_until_baseline (grade 2 or 3). Not hyperthyroidism (Table 4.1.2). magent does not assay TSH/FT4. Not a medical device, not a diagnosis, not a levothyroxine dose.
Paid test badge: not yet. The checks above are free: we call the tool without paying and read the payment request it sends back. The Verified badge needs paid calls whose answers match the promised output, and nobody can buy a badge.
Endpoint
POST https://api.magentlab.com/api/calc/irae_hypothyroidism
| Category | Everything else |
|---|---|
| Provider host | api.magentlab.com |
| Networks | eip155:8453 |
| Payment schemes | exact |
| Self-reported calls, 30 days | 0 from 0 payers (the provider's figure, not ours) |
Our checks, last 30 days
| Day | Result | HTTP | Asked | Time |
|---|---|---|---|---|
| 2026-09-28 | valid payment request | 402 | $0.007 | 302 ms |
Example input (from the provider)
{
"body": {
"items": [
{
"moderate_symptoms": false,
"severe_or_life_threatening": false,
"tsh_miu_l": 8,
"unable_to_perform_adl": false
},
{
"moderate_symptoms": false,
"severe_or_life_threatening": false,
"tsh_miu_l": 8,
"unable_to_perform_adl": false
}
]
},
"method": "POST",
"type": "http"
}
Promised output schema (from the provider)
{
"$schema": "https://json-schema.org/draft/2020-12/schema",
"properties": {
"input": {
"additionalProperties": false,
"properties": {
"body": {
"additionalProperties": false,
"properties": {
"items": {
"items": {
"properties": {
"moderate_symptoms": {
"description": "Moderate symptoms with ability to perform ADL as assigned by the caller (Brahmer 2018 Table 4.1.1 grade 2). true or false. When true and no grade 3 flag is true, grade is 2. magent does not examine the patient.",
"type": "boolean"
},
"severe_or_life_threatening": {
"description": "Severe symptoms, medically significant or life-threatening consequences as assigned by the caller (Brahmer 2018 Table 4.1.1 grade 3-4, returned as grade 3). true or false. When true, grade is 3. magent does not examine the patient.",
"type": "boolean"
},
"tsh_miu_l": {
"description": "TSH in mIU/L (0.01-150; Brahmer 2018 Table 4.1.1 primary hypothyroidism). Persistently TSH >10 mIU/L is grade 2 unless a grade 3 flag is true; TSH 10 is this band. TSH <10 mIU/L with no moderate or severe flags is grade 1. magent does not assay TSH.",
"type": "number"
},
"unable_to_perform_adl": {
"description": "Unable to perform ADL as assigned by the caller (Brahmer 2018 Table 4.1.1 grade 3-4, returned as grade 3). true or false. When true, grade is 3. magent does not assess ADL.",
"type": "boolean"
}
},
"required": [
"tsh_miu_l",
"moderate_symptoms",
"severe_or_life_threatening",
"unable_to_perform_adl"
],
"type": "object"
},
"maxItems": 25,
"minItems": 1,
"type": "array"
}
},
"required": [
"items"
],
"type": "object"
},
"headers": {
"additionalProperties": {
"type": "string"
},
"type": "object"
},
"method": {
"const": "POST",
"type": "string"
},
"type": {
"const": "http",
"type": "string"
}
},
"required": [
"type",
"method"
],
"type": "object"
},
"output": {
"properties": {
"example": {
"type": "object"
},
"type": {
"type": "string"
}
},
"required": [
"type"
],
"type": "object"
}
},
"required": [
"input"
],
"type": "object"
}