Lyon 2020 HFA-ICOS baseline CV risk before VEGF inhibitors or VEGF TKIs

Lyon 2020 HFA-ICOS baseline CV risk before VEGF inhibitors or VEGF TKIs. Very high if heart failure/cardiomyopathy or arterial vascular disease. High if venous thrombosis, LVEF <50%, QTc >=480 ms, age >=75, hypertension, prior anthracycline, or >=5 medium points. Medium if 2-4 medium points. Guide <2% / 2-9% / 10-19% / >=20%. Not a device or treatment order.

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Endpoint

POST https://api.magentlab.com/api/calc/hfa_icos_vegf

Our checks, last 30 days

Example input (from the provider)

{
  "body": {
    "items": [
      {
        "age_years": 50,
        "arrhythmia": false,
        "arterial_vascular_disease": false,
        "ckd": false,
        "current_or_significant_smoker": false,
        "diabetes": false,
        "elevated_bnp": false,
        "elevated_troponin": false,
        "heart_failure_or_cardiomyopathy": false,
        "hyperlipidemia": false,
        "hypertension": false,
        "lvef_percent": 60,
        "obesity": false,
        "prior_anthracycline": false,
        "prior_left_chest_or_mediastinal_rt": false,
        "proteinuria": false,
        "qtc_ms": 400,
        "sex": "female",
        "venous_thrombosis": false
      },
      {
        "age_years": 50,
        "arrhythmia": false,
        "arterial_vascular_disease": false,
        "ckd": false,
        "current_or_significant_smoker": false,
        "diabetes": false,
        "elevated_bnp": false,
        "elevated_troponin": false,
        "heart_failure_or_cardiomyopathy": false,
        "hyperlipidemia": false,
        "hypertension": false,
        "lvef_percent": 60,
        "obesity": false,
        "prior_anthracycline": false,
        "prior_left_chest_or_mediastinal_rt": false,
        "proteinuria": false,
        "qtc_ms": 400,
        "sex": "female",
        "venous_thrombosis": false
      }
    ]
  },
  "method": "POST",
  "type": "http"
}

Promised output schema (from the provider)

{
  "$schema": "https://json-schema.org/draft/2020-12/schema",
  "properties": {
    "input": {
      "additionalProperties": false,
      "properties": {
        "body": {
          "additionalProperties": false,
          "properties": {
            "items": {
              "items": {
                "properties": {
                  "age_years": {
                    "description": "Integer age in years (18-100) as assigned by the caller. Lyon 2020 VEGF-inhibitor table: >=75 High; 65-74 Medium 1; <65 no age points. Bands are exclusive. magent does not read an identity document.",
                    "type": "integer"
                  },
                  "arrhythmia": {
                    "description": "Arrhythmia (atrial fibrillation, atrial flutter, ventricular tachycardia, or ventricular fibrillation) as assigned by the caller (Lyon 2020 VEGF-inhibitor table, Medium 2). true or false.",
                    "type": "boolean"
                  },
                  "arterial_vascular_disease": {
                    "description": "Arterial vascular disease: IHD, PCI, CABG, stable angina, TIA, stroke, or PVD as one caller bool (Lyon 2020 VEGF-inhibitor table, very high). true or false. magent does not diagnose vascular disease.",
                    "type": "boolean"
                  },
                  "ckd": {
                    "description": "Chronic kidney disease (eGFR <60 mL/min/1.73 m2) as assigned by the caller (Lyon 2020 VEGF-inhibitor table, Medium 1). true or false. magent does not compute eGFR.",
                    "type": "boolean"
                  },
                  "current_or_significant_smoker": {
                    "description": "Current smoker or significant smoking history as assigned by the caller (Lyon 2020 VEGF-inhibitor table, Medium 1). true or false.",
                    "type": "boolean"
                  },
                  "diabetes": {
                    "description": "Diabetes mellitus (glycated haemoglobin >7.0% or >53 mmol/mol, or on treatment) as assigned by the caller (Lyon 2020 VEGF-inhibitor table, Medium 1). true or false.",
                    "type": "boolean"
                  },
                  "elevated_bnp": {
                    "description": "Elevated baseline BNP or NT-proBNP above the local laboratory upper limit of normal as assigned by the caller (Lyon 2020 VEGF-inhibitor table, Medium 1). true or false. magent does not assay BNP.",
                    "type": "boolean"
                  },
                  "elevated_troponin": {
                    "description": "Elevated baseline troponin above the local laboratory upper limit of normal as assigned by the caller (Lyon 2020 VEGF-inhibitor table, Medium 1). true or false. magent does not assay troponin.",
                    "type": "boolean"
                  },
                  "heart_failure_or_cardiomyopathy": {
                    "description": "Heart failure or cardiomyopathy (Lyon 2020 VEGF-inhibitor table, very high). Caller-assigned. true or false.",
                    "type": "boolean"
                  },
                  "hyperlipidemia": {
                    "description": "Hyperlipidemia (non-HDL cholesterol >3.8 mmol/L or >145 mg/dL) as assigned by the caller (Lyon 2020 VEGF-inhibitor table, Medium 1). true or false. magent does not convert lipid units.",
                    "type": "boolean"
                  },
                  "hypertension": {
                    "description": "Hypertension (SBP >140 mmHg or DBP >90 mmHg, or on treatment) as assigned by the caller (Lyon 2020 VEGF-inhibitor table, High). true or false. magent does not read a blood-pressure cuff.",
                    "type": "boolean"
                  },
                  "lvef_percent": {
                    "description": "Baseline left-ventricular ejection fraction, integer percent 10-80, as assigned by the caller. <50 High; 50-54 Medium 2; >=55 no LVEF points. magent does not read an echocardiogram.",
                    "type": "integer"
                  },
                  "obesity": {
                    "description": "Obesity (BMI >30 kg/m2) as assigned by the caller (Lyon 2020 VEGF-inhibitor table, Medium 1). true or false. magent does not compute BMI.",
                    "type": "boolean"
                  },
                  "prior_anthracycline": {
                    "description": "Prior anthracycline exposure as assigned by the caller (Lyon 2020 VEGF-inhibitor table, High). true or false.",
                    "type": "boolean"
                  },
                  "prior_left_chest_or_mediastinal_rt": {
                    "description": "Prior radiotherapy to the left chest or mediastinum as assigned by the caller (Lyon 2020 VEGF-inhibitor table, Medium 1). true or false.",
                    "type": "boolean"
                  },
                  "proteinuria": {
                    "description": "Proteinuria as assigned by the caller (Lyon 2020 VEGF-inhibitor table, Medium 1). true or false.",
                    "type": "boolean"
                  },
                  "qtc_ms": {
                    "description": "Baseline QTc in milliseconds, integer 300-700, as assigned by the caller. >=480 High; men 450-479 Medium 2; women 460-479 Medium 2. magent does not measure QTc.",
                    "type": "integer"
                  },
                  "sex": {
                    "description": "male or female as assigned by the caller. Used only for the sex-specific borderline QTc Medium 2 band (men 450-479 ms; women 460-479 ms).",
                    "type": "string"
                  },
                  "venous_thrombosis": {
                    "description": "Venous thrombosis (DVT or PE) as assigned by the caller (Lyon 2020 VEGF-inhibitor table, High). true or false.",
                    "type": "boolean"
                  }
                },
                "required": [
                  "age_years",
                  "sex",
        

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