Look up a protein in UniProtKB by accession (e.g
Look up a protein in UniProtKB by accession (e.g. "P04637", "Q9Y6K9", "P0DTC2"). Returns the entry id, reviewed (Swiss-Prot) flag, recommended + alternative protein names, gene names, organism + taxid, sequence length and molecular weight, the curated function description, subcellular locations, Gene Ontology terms (id + term + aspect: biological_process / molecular_function / cellular_component), PDB structure ids, and keywords. Bioinformatics, structural biology, drug-target research, education. Gene-centric sibling: /api/bio/gene. CC-BY UniProt data.
Paid test badge: not yet. The checks above are free: we call the tool without paying and read the payment request it sends back. The Verified badge needs paid calls whose answers match the promised output, and nobody can buy a badge.
Endpoint
GET https://2s.io/api/bio/protein
| Category | Search and research |
|---|---|
| Provider host | 2s.io |
| Networks | eip155:8453, solana:5eykt4UsFv8P8NJdTREpY1vzqKqZKvdp |
| Payment schemes | exact |
| Self-reported calls, 30 days | 1 from 1 payers (the provider's figure, not ours) |
Our checks, last 30 days
| Day | Result | HTTP | Asked | Time |
|---|---|---|---|---|
| 2026-09-24 | valid payment request | 402 | $0.0036 | 236 ms |
Example input (from the provider)
{
"method": "GET",
"queryParams": {
"accession": "P04637"
},
"type": "http"
}
Promised output schema (from the provider)
{
"$schema": "https://json-schema.org/draft/2020-12/schema",
"properties": {
"input": {
"properties": {
"method": {
"const": "GET"
},
"queryParams": {
"properties": {
"accession": {
"description": "UniProtKB accession, e.g. \"P04637\".",
"type": "string"
}
},
"required": [
"accession"
]
},
"type": {
"const": "http"
}
},
"required": [
"type",
"method",
"queryParams"
],
"type": "object"
}
},
"required": [
"input"
],
"type": "object"
}