{"slug":"api-magentlab-com-api-calc-hep-1fdac2","title":"Cuker 2010 HEP score","host":"api.magentlab.com","method":"POST","resource":"https://api.magentlab.com/api/calc/hep","category":"other","description":"Cuker 2010 HEP score: eight features with signed weights (range -16 to 19). Magnitude of platelet fall, typical- or rapid-onset timing, nadir, thrombosis (at most one), SQ heparin skin necrosis, IV-bolus systemic reaction, bleeding, and other causes (select all; no other cause +3). Cutoff 2 was 100%","price_listed":0.005,"price_asked":0.007,"state":"overcharges","state_label":"Asked 1.4x its listed price for its own example","checks_7d":1,"answered_7d":1,"latency_ms_median":367,"reported_calls_30d":0,"reported_payers_30d":0,"networks":["eip155:8453"],"badge":"unverified","paid_checks_7d":0,"paid_ok_7d":0,"example_input":{"body":{"items":[{"bleeding":false,"chronic_thrombocytopenia":false,"cpb_96h":false,"intra_arterial_device":false,"magnitude":"gt_50","nadir":"gt_20","new_drug_thrombocytopenia":false,"no_other_cause":true,"overt_dic":false,"severe_infection":false,"skin_necrosis":false,"systemic_reaction":false,"thrombosis":"typical_new_ge_4d","timing":"typical_5_10"},{"bleeding":false,"chronic_thrombocytopenia":false,"cpb_96h":false,"intra_arterial_device":false,"magnitude":"gt_50","nadir":"gt_20","new_drug_thrombocytopenia":false,"no_other_cause":true,"overt_dic":false,"severe_infection":false,"skin_necrosis":false,"systemic_reaction":false,"thrombosis":"typical_new_ge_4d","timing":"typical_5_10"}]},"method":"POST","type":"http"},"output_schema":{"$schema":"https://json-schema.org/draft/2020-12/schema","properties":{"input":{"additionalProperties":false,"properties":{"body":{"additionalProperties":false,"properties":{"items":{"items":{"properties":{"bleeding":{"description":"Presence of bleeding, petechiae, or extensive bruising (Cuker 2010). true scores -1; false scores 0.","type":"boolean"},"chronic_thrombocytopenia":{"description":"Presence of a chronic thrombocytopenic disorder (Cuker 2010 other causes; select all that apply). true scores -1. Mutually exclusive with no_other_cause true.","type":"boolean"},"cpb_96h":{"description":"Cardiopulmonary bypass within the previous 96 hours (Cuker 2010). true scores -1. Mutually exclusive with no_other_cause true.","type":"boolean"},"intra_arterial_device":{"description":"Indwelling intra-arterial device (Cuker 2010 examples: IABP, VAD, ECMO). true scores -2. Mutually exclusive with no_other_cause true.","type":"boolean"},"magnitude":{"description":"Caller-assigned Cuker 2010 magnitude of platelet fall (peak to nadir since heparin exposure). lt_30 (<30%) scores -1; 30_to_50 (30-50%) scores 1; gt_50 (>50%) scores 3. magent does not grade platelet counts.","type":"string"},"nadir":{"description":"Caller-assigned Cuker 2010 nadir platelet count. le_20 (≤20 ×10^9/L) scores -2; gt_20 (>20 ×10^9/L) scores 2. magent does not take a raw platelet count.","type":"string"},"new_drug_thrombocytopenia":{"description":"Newly initiated non-heparin medication known to cause thrombocytopenia (Cuker 2010). true scores -2. Mutually exclusive with no_other_cause true.","type":"boolean"},"no_other_cause":{"description":"No other apparent cause of thrombocytopenia (Cuker 2010). true scores 3. Must be false if any other-cause flag is true.","type":"boolean"},"overt_dic":{"description":"Overt DIC as assigned by the caller (Cuker 2010: fibrinogen <100 mg/dL and D-dimer >5.0 μg/mL). true scores -2. magent does not assay fibrinogen or D-dimer. Mutually exclusive with no_other_cause true.","type":"boolean"},"severe_infection":{"description":"Severe infection as an other cause of thrombocytopenia (Cuker 2010). true scores -2. Mutually exclusive with no_other_cause true.","type":"boolean"},"skin_necrosis":{"description":"Skin necrosis at subcutaneous heparin injection sites (Cuker 2010). true scores 3; false scores 0. magent does not examine the skin.","type":"boolean"},"systemic_reaction":{"description":"Acute systemic reaction after intravenous heparin bolus (Cuker 2010). true scores 2; false scores 0.","type":"boolean"},"thrombosis":{"description":"Caller-assigned Cuker 2010 thrombosis (select at most one). none scores 0. Typical-onset: typical_new_ge_4d (new VTE or ATE ≥4 days after heparin) 3; typical_progression (progression of preexisting VTE or ATE while receiving heparin) 2. Rapid-onset: rapid_new (new VTE or ATE after heparin) 3; rapid_progression 2.","type":"string"},"timing":{"description":"Caller-assigned Cuker 2010 timing. Typical-onset: typical_lt_4 (fall begins <4 days) -2; typical_day_4 (day 4) 2; typical_5_10 (days 5-10) 3; typical_11_14 (days 11-14) 2; typical_gt_14 (>14 days) -1. Rapid-onset after re-exposure within 100 days: rapid_lt_48h (<48 h) 2; rapid_gt_48h (>48 h) -1. magent does not infer day of onset.","type":"string"}},"required":["magnitude","timing","nadir","thrombosis","skin_necrosis","systemic_reaction","bleeding","chronic_thrombocytopenia","new_drug_thrombocytopenia","severe_infection","overt_dic","intra_arterial_device","cpb_96h","no_other_cause"],"type":"object"},"maxItems":25,"minItems":1,"type":"array"}},"required":["items"],"type":"object"},"headers":{"additionalProperties":{"type":"string"},"type":"object"},"method":{"const":"POST","type":"string"},"type":{"const":"http","type":"string"}},"required":["type","method"],"type":"object"},"output":{"properties":{"example":{"type":"object"},"type":{"type":"string"}},"required":["type"],"type":"object"}},"required":["input"],"type":"object"},"history":[{"day":"2026-09-28","reachable":true,"status":402,"valid_402":true,"asked_usdc":0.007,"price_match":false,"latency_ms":367,"error":null}],"description_full":"Cuker 2010 HEP score: eight features with signed weights (range -16 to 19). Magnitude of platelet fall, typical- or rapid-onset timing, nadir, thrombosis (at most one), SQ heparin skin necrosis, IV-bolus systemic reaction, bleeding, and other causes (select all; no other cause +3). Cutoff 2 was 100% sensitive / 60% specific vs the expert panel. Not a HIT diagnosis or 4Ts score. magent does not assay SRA or ELISA.","last_updated":"2026-09-28T15:13:23.402Z","schemes":["exact"]}